A global comparison of the human and T. brucei degradomes gives insights about possible parasite drug targets.

We performed a genome-level computational study of sequence and structure similarity, the latter using crystal structures and models, of the proteases of Homo sapiens and the human parasite Trypanosoma brucei.Using sequence and structure similarity networks to summarize the results, we constructed global views that show visually the relative abunda

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Expression Atlas of the Deubiquitinating Enzymes in the Adult Mouse Retina, Their Evolutionary Diversification and Phenotypic Roles.

Ubiquitination is a relevant cell regulatory mechanism to determine protein fate and function.Most data has focused on the role of ubiquitin as a tag molecule to target substrates to proteasome degradation, and on its impact in the control Thermometer Probes of cell cycle, protein homeostasis and cancer.Only recently, systematic assays have pointed

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WHAT HAPPENS DURING THOSE LONG HOURS NEXT TO THE ROAD? AN EXPLORATORY STUDY OF THREE INFORMAL DAY LABOUR HIRING SITES IN TSHWANE

Valenzuela (2002) calls people who congregate at informal pick-up points to seek for work for the day, by the hour or for a specific job, day labourers and the pick-up points hiring sites.These hiring sites are described as Fuse Holder open-air geographical locations, such as street corners, pavements, car parking lots and factory gates (Blaauw, 20

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Problem Intrinsik DALAM AGENDA PEMBANGUNAN BERKELANJUTAN: Analisis FILSAFAT POLITIK TERHADAP PENGELOLAAN LINGKUNGAN DI INDONESIA PASCA REFORMASI

Penelitian ini bertujuan untuk melakukan analisis kritis atas problem intrinsik gagasan pembangunan berkelanjutan di Indonesia, khususnya terkait dengan politik pengelolaan lingkungan di Indonesia pasca reformasi.Hal ini didasarkan pada fakta bahwa tingkat kerusakan lingkungan, khususnya sumber daya alam di Indonesia, masih sangat tinggi.Penelitian

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